For millions of people living with depression, finding relief isn’t as simple as taking a single pill. Many patients try one, two, even three medications without seeing meaningful change. This frustrating cycle is more than just bad luck—it may be a sign of treatment-resistant depression, a condition that requires a different kind of support.
What Is Treatment-Resistant Depression?
Treatment-resistant depression (TRD) is diagnosed when a person with major depressive disorder doesn’t respond to at least two different antidepressant medications, each taken at an appropriate dose and duration. If you’ve been through several rounds of medications with little to no improvement, you may be dealing with TRD—and you’re not alone.
According to research, up to one-third of patients with depression don’t find adequate relief from traditional antidepressants. It’s not a reflection of willpower, motivation, or effort. Rather, it suggests that your brain may need a more targeted intervention—one that goes beyond chemistry alone.
Why Antidepressants Aren’t Always Enough
Antidepressants work by shifting levels of neurotransmitters like serotonin, dopamine, or norepinephrine. However, their effects are systemic, meaning they impact the entire body—not just the parts of the brain responsible for mood. That’s why some people experience side effects like weight changes, sexual dysfunction, insomnia, or emotional blunting.
In cases of treatment-resistant depression, the issue may lie in the brain’s electrical activity rather than chemical imbalances alone. If medications haven’t reached the source of your symptoms, no dosage adjustment will fully address the problem.
That’s where Transcranial Magnetic Stimulation (TMS) comes in.
How TMS Treats Treatment-Resistant Depression Differently
TMS is a non-invasive, FDA-cleared treatment for treatment-resistant depression that stimulates the brain directly using magnetic pulses. Instead of affecting the whole body like medication, TMS zeroes in on the prefrontal cortex—a key region involved in emotional regulation and decision-making.
Key Benefits of TMS for Treatment-Resistant Depression
- Precise, targeted therapy: TMS delivers magnetic pulses only where they’re needed—at the source of the issue in the brain.
- No systemic side effects: Because it doesn’t travel through the bloodstream, TMS avoids the common side effects associated with antidepressants.
- Safe and well-tolerated: Patients remain awake and alert during each session, which typically lasts 20 minutes or less.
- Insurance-covered: Most major insurers, including Medicare, cover TMS for eligible patients with TRD.
Over the course of 4 to 6 weeks, patients undergo regular TMS sessions, gradually restoring healthier brain activity patterns associated with mood improvement and emotional clarity.
Is TMS Right for You?
If you or someone you love has been struggling with treatment-resistant depression, you may feel like you’ve exhausted every option. TMS offers new hope, especially for those who:
- Have tried at least two antidepressants without significant relief
- Experience side effects that make long-term medication use difficult
- Want a non-drug option that addresses depression at its neurological source
At SEBERS Medical, we’re proud to distribute the most advanced, research-backed TMS systems available today. We partner with clinics, providers, and practices across the country who want to bring high-quality TMS care to their communities.
Reclaim Control Over Your Mental Health
Depression doesn’t always respond to the first treatment—or even the second. That doesn’t mean recovery is out of reach. With the right tools, including innovative therapies like TMS, relief from treatment-resistant depression is possible.
We believe in solutions that go beyond symptom management. Whether you’re a patient looking for answers or a clinic ready to expand your mental health services, SEBERS Medical is here to help you take the next step forward.
Learn more about our TMS technology and find out how Blossom TMS can support individuals facing treatment-resistant depression by visiting:
SEBERS Medical
230 S Broad Street, 17th Floor, Philadelphia, PA 19102
Phone: 833.3BUY.TMS (+1.833.3289.867)
Email: Sales@sebersmedical.com
